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476-66-4 - Ellagic acid hydrate, 97%, may cont. up to 12% water - 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone hydrate - A15722 - Alfa Aesar

A15722 Ellagic acid hydrate, 97%, may cont. up to 12% water

Numéro de CAS
476-66-4
Synonymes
4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone hydrate

Conditionnement Prix ($) Quantité Disponibilité
5g 40,20
25g 143,00
100g 443,00
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Ellagic acid hydrate, 97%, may cont. up to 12% water

MDL
MFCD00149494
EINECS
207-508-3

Propriétés chimiques

Formule
C14H6O8•xH2O
Poids moleculaire
302.20(anhy)
Point de fusion
450° dec.
Sensibilité
Air & Light Sensitive
Solubilité
Slightly soluble in water. Soluble in 1M sodium hydroxide (10 mg/ml), EtOH, and pyridine.

Applications

Ellagic acid used as selective, ATP-competitive inhibitor of casein kinase 2. Exhibits antitumor activity and inhibits glutathione S-transferase. It is also used as a Topo I and II, FGR, GSK, and PKA inhibitor.Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma.Contact activation in blood coagulation.

Notes

Air sensitive and light sensitive. Store under dry inert gas. Store in cool dry place in tightly closed container. Store in dark and away form air.

Références bibliographiques

Patrice Njomnang Soh: Benoît Witkowski; David Olagnier; Marie-Laure Nicolau; Maria-Concepcion Garcia-Alvarez; Antoine Berry; and Françoise Benoit-Vical. In Vitro and In Vivo Properties of Ellagic Acid in Malaria Treatment. Antimicrob. Agents Chemother. 2009, 31100-1106.

Sungwoo Kim; Satoru K. Nishimoto; Joel D. Bumgardnerd; Warren O. Haggardd; M. Waleed Gabere; Yunzhi Yang. A chitosan/β-glycerophosphate thermo-sensitive gel for the delivery of ellagic acid for the treatment of brain cancer. Biomaterials. 2010, 31 (14), 4157-4166.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,3547
Beilstein
47549
Code tarifaire harmonisé
2932.20
TSCA
No
RTECS
DJ2620000

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Consulté récemment

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Analytique et matériel de laboratoire