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4431-00-9 - Aurintricarboxylic acid - A15905 - Alfa Aesar

A15905 Aurintricarboxylic acid

Numéro CAS
4431-00-9
Synonymes

Dimensions Prix ($) Quantité Disponibilité
5g 31,60
25g 97,20
100g 311,00
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Aurintricarboxylic acid

MDL
MFCD00011663
EINECS
224-628-1

Propriétés chimiques

Formule
C22H14O9
Poids formulaire
422.35
Point de fusion
>300°
Solubilité
Insoluble in water.

Applications

Aurintricarboxylic acid is employed as a powerful inhibitor of cellular processes, including apoptosis, that are dependent on the formation of protein-nucleic acid complexes. It binds to a FGF and reduces its angiogenic activity. Aurintricarboxylic Acid has been shown to inhibit apoptotic cell death in various cell types induced by a variety of factors. It Inhibits protein-nucleic acid interactions. It stimulates the tyrosine phosphorylation of MAP kinases.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong bases and strong oxidizing agents.

Références bibliographiques

Richard B. Hallick.; Barry K. Chelm.; Patrick W. Gray.; Emil M. Orozco Jr. Use of aurintricarboxylic acid as an inhibitor of nucleases during nucleic acid isolation. Nucl. Acids Res. 1979, 4 (9),3055-3064.

Jill M. Roberts-Lewis.; Val R. Marcy.; Yonghua Zhao.; Jeffry L. Vaught.; Robert Siman.; Michael E. Lewis. Aurintricarboxylic Acid Protects Hippocampal Neurons from NMDA-and Ischemia-Induced Toxicity In Vivo. Journal of Neurochemistry. 1993, 61 (1), 378-381.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
2228904
Code tarifaire harmonisé
2918.99
TSCA
Yes
RTECS
GU4790000

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire