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42348-86-7 - 5-Chloro-1-indanone, 99% - A18308 - Alfa Aesar

A18308 5-Chloro-1-indanone, 99%

Numéro CAS
42348-86-7
Synonymes

Dimensions Prix ($) Quantité Disponibilité
1g 46,50
5g 154,00
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5-Chloro-1-indanone, 99%

MDL
MFCD00041456

Propriétés chimiques

Formule
C9H7ClO
Poids formulaire
166.61
Point de fusion
92-96°
Point d'ébullition
124-125°/3mm
Solubilité
Insoluble in water.

Applications

5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Références bibliographiques

Mark T. DuPriest; Charles L.Schmidt; Daniel Kuzmich; Stanly B.Williams. A facile synthesis of 7-halo-5H-indeno[1,2-b]pyridines and -pyridin-5-ones. J. Org. Chem. 1986, 51,(11), 2021-2023.

 

Tomas Pena Ruiz; Manuel Fernandez Gomez; Juan Jesus Lopez Gonzalez; Anna E.Koziol. Weak hydrogen-, halogen- and stacking π?π bonding in crystalline 5-chloro-1-indanone. An analysis by using X-ray diffraction, vibrational spectroscopy and theoretical methods. Chemical Physics. 2006, 320,(2-3), 164-180.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
1448000
Code tarifaire harmonisé
2914.70
TSCA
Yes

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