Consentement d'utilisation des Cookies

J'accepte. Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

A18627 Indole-5-carboxylic acid, 98%

Numéro de CAS
1670-81-1
Synonymes

Stock No. Conditionnement Prix ($) Quantité Disponibilité
A18627-03 1g 35,30
A18627-06 5g 115,00
A18627-14 25g 488,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Indole-5-carboxylic acid, 98%

MDL
MFCD00005678
EINECS
216-799-6

Propriétés chimiques

Formule
C9H7NO2
Poids moleculaire
161.16
Point de fusion
208-212°
Storage & Sensitivity
Ambient temperatures.
Solubilité
Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol.

Applications

Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Références bibliographiques

Eduard Dolusi? et. al. Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators. Journal of medicinal and pharmaceutical chemistry, 2011, 54 (15), 5320-5334.

Mikaël Brasse; Jonathan A Ellman; Robert G Bergman. A facile, metal- and solvent-free, autoxidative coupling of quinolines with indoles and pyrroles. Chemical Communications, 2011, 47 (17), 5019-5021.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
124391
Code tarifaire harmonisé
2933.99
TSCA
No

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire