Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

75-05-8 - Acetonitrile, 99% - Methyl cyanide - Cyanomethane - A19862 - Alfa Aesar

A19862 Acetonitrile, 99%

Numéro CAS
75-05-8
Synonymes
Methyl cyanide
Cyanomethane

Dimensions Prix ($) Quantité Disponibilité
500ml 29,66
2500ml 87,96
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Acetonitrile, 99%

MDL
MFCD00001878
EINECS
200-835-2

Propriétés chimiques

Formule
C2H3N
Poids formulaire
41.05
Point de fusion
-48°
Point d'ébullition
80-82°
Point d'éclair
5°(41°F)
Densité
0.786
Indice de réfraction
1.3440
Solubilité
Miscible with water, alcohols, ethers, acetone, chloroform, carbon tetrachloride and ethylene chloride. Immiscible with saturated hydrocarbons (petroleum fractions).

Applications

Acetonitrile is utilized as a polar aprotic solvent in organic synthesis, and in the purification of butadiene. It is used in all the analytical laboratories as a major component of mobile phase in High Performance Liquid Chromatography (HPLC) and in Liquid Chromatography - Mass Spectrometry (LC-MS). It is used for the extraction of fatty acids, spinning fibers and casting and molding of plastic materials. Aqueous two-phase systems based on acetonitrile and carbohydrates play an important character in the extraction and purification of biomolecules called vanillins. It acts as a stabilizer for the chlorinated solvents, and finds use in the production of DNA oligonucleotides.

Notes

Incompatible with alkali metals, acids, bases, reducing agents and oxidizing agents. Highly flammable. Store it away from heat, sparks, and flame exposure.

Références bibliographiques

Polar aprotic solvent for a wide variety of reactions, including nucleophilic substitutions, oxidations, reductions and organometallic reactions. Widely used with crown ethers for the generation of 'naked' anions from their salts; see, e.g. 18-Crown-6, A11249 . Preferred solvent for RuO4 oxidations, due to its coordinating ability; see Ruthenium(III)­ chloride hydrate, 11043 .

Undergoes the Ritter reaction with alcohols or olefins in the presence of acid to give N-substituted acetamides. For benzylic alcohols, modified conditions employing boron trifluoride etherate give high yields: Synth. Commun., 24, 601 (1994). For an example, see 4-Methyl­benzyl­ alcohol, A15315 .

For use in the mild conversion of amides to nitriles, see Benzamide, A10501 .

Cardoso, G. B.; Mourao, T.; Pereira, F. M.; Freire, M. G.; Fricks, A. T.; Soares, C. M. F.; Lima, A. S. Aqueous two-phase systems based on acetonitrile and carbohydrates and their application to the extraction of vanillin. 2013, 104 (5), 106-113.

Xu, K.; Zhu, L.; Zhang, A.; Jiang, G.; Tang, H. A peculiar cyclic voltammetric behavior of polyaniline in acetonitrile and its application in ammonia vapor sensor. 2007, 608 (2), 141-147.

Lam, T. W.; Zhang, H.; Siu, S. K. Reductions of Oxygen, Carbon Dioxide, and Acetonitrile by the Magnesium(II)/Magnesium(I) Couple in Aqueous Media: Theoretical Insights from a Nano-Sized Water Droplet. J. Phys. Chem. A 2015, 119 (12), 2780-2792.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H225-H302-H312-H332-H319

Highly flammable liquid and vapour. Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes serious eye irritation.

Mentions de prudence: P210-P261-P280-P240-P241-P303+P361+P353-P305+P351+P338-P304+P340-P301+P312-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,70
Beilstein
741857
Classe de danger
3
Groupe d'emballage
II
Code tarifaire harmonisé
2926.90
TSCA
Yes
RTECS
AL7700000

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire