Consentement d'utilisation des Cookies

J'accepte. Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

4241-27-4 - 3-Cyano-6-methyl-2-pyridone, 98% - 3-Cyano-2-hydroxy-6-methylpyridine - 2-Hydroxy-6-methylnicotinonitrile - B20188 - Alfa Aesar

B20188 3-Cyano-6-methyl-2-pyridone, 98%

Numéro de CAS
4241-27-4
Synonymes
3-Cyano-2-hydroxy-6-methylpyridine
2-Hydroxy-6-methylnicotinonitrile

Conditionnement Prix ($) Quantité Disponibilité
10g 56,10
50g 220,00
250g 919,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

3-Cyano-6-methyl-2-pyridone, 98%

MDL
MFCD00006013
EINECS
224-202-5

Propriétés chimiques

Formule
C7H6N2O
Poids moleculaire
134.14
Point de fusion
ca 298° dec.
Solubilité
Soluble in water at 20°C, 2.38 g/L.

Applications

3-Cyano-6-methyl-2(1H)-pyridinone is a reactant used in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. 3-It has also been used in the preparation of the N3?-pyridyl thiamine, a potent in vitro thiamine antagonist.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Références bibliographiques

Allen A. Thomas, et al. Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.Bioorg Med Chem Lett.2008,18(6), 2206-2210.

Munakata M, et al. Construction of three-dimensional supramolecular coordination copper (I) compounds with channel structures hosting a variety of anions by changing the hydrogen-bonding mode and distances.J. Am. Chem. Soc.1996,118(13), 3117-24.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
120412
Code tarifaire harmonisé
2933.39
TSCA
Yes

Recommandé

  • H62858

    N-Benzyloxycarbonylglycine methyl ester, 98%
  • J60364

    Chenodeoxycholic acid
  • 32281

    Benzenesulfonic acid, Technical Grade
  • H52629

    5-Amino-2-(hydroxymethyl)benzeneboronic acid hemiester hydrochloride, 95%
  • A12470

    2-Vinylnaphthalene, 97%

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire