Consentement d'utilisation des Cookies

J'accepte. Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

119-65-3 - Isoquinoline, 97% - B21279 - Alfa Aesar

B21279 Isoquinoline, 97%

Numéro de CAS
119-65-3
Synonymes

Conditionnement Prix ($) Quantité Disponibilité
100g 58,10
500g 186,00
2500g 591,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Isoquinoline, 97%

MDL
MFCD00006898
EINECS
204-341-8

Propriétés chimiques

Formule
C9H7N
Poids moleculaire
129.16
Point de fusion
24-27°
Point d'ébullition
241-243°
Point d'éclair
107°(225°F)
Densité
1.090
Indice de réfraction
1.6245
Solubilité
Soluble in water (5g/L).

Applications

Isoquinoline is used in the manufacture of dyes, paints, antifungal. It is also used as a solvent for the extraction of resins and terpenes.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Références bibliographiques

Maria Chrzanowska.; Maria D. Rozwadowska. Asymmetric Synthesis of Isoquinoline Alkaloids. Chem. Rev. 2004, 104, (7), 3341-3370.

Ryoji. Noyori.; Masako. Ohta.; Yi. Hsiao.; Masato. Kitamura.; Tetsuo. Ohta.; Hidemasa. Takaya. Asymmetric synthesis of isoquinoline alkaloids by homogeneous catalysis. J. Am. Chem. Soc. 1986, 108, (22), 7117-7119.

Reacts with various acid halides in the presence of CN- to give "Reissert compounds" (1-cyano-2-acyl 1,2-dihydro derivatives). For reviews, see: Chem. Rev., 55, 511 (1955); Adv. Het. Chem., 9, 1 (1968); 24, 187 (1979). 1-Alkylisoquinolines can be prepared by alkylation of the Li or Na derivatives of Reissert compounds: Org. Synth. Coll., 4, 641 (1963); 6, 115 (1988). For formation of Reissert compounds from a variety of carbonyl, sulfonyl and phosphoryl halides under milder, phase-transfer conditions, see: Synthesis, 497 (1977). For 'direct' cyanation by a modified Reissert procedure in the presence of tosyl chloride followed by DBU, see: J. Org. Chem., 49, 4056 (1984).

A one-step synthesis of 1-nitroisoquinoline has been reported in which isoquinoline reacts with KNO2 in the presence of acetic anhydride and DMSO. The reaction is considered to be analogous to the Pfitzner-Moffatt oxidation (see Dimethyl­ sulfoxide, A13280): J. Chem. Soc., Perkin 1, 1777 (1996).

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H311-H315-H319

Harmful if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation.

Mentions de prudence: P280-P305+P351+P338-P301+P312a-P321-P405-P501a

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,5222
Beilstein
107549
Classe de danger
6.1
Groupe d'emballage
II
Code tarifaire harmonisé
2933.49
TSCA
Yes
RTECS
NW6825000

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire