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2156-56-1 - Sodium dichloroacetate, 97% - Dichloroacetic acid sodium salt - B21827 - Alfa Aesar

B21827 Sodium dichloroacetate, 97%

Numéro CAS
2156-56-1
Synonymes
Dichloroacetic acid sodium salt

Dimensions Prix ($) Quantité Disponibilité
10g 49,44
50g 211,50
250g 774,90
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Sodium dichloroacetate, 97%

MDL
MFCD00070489
EINECS
218-461-3

Propriétés chimiques

Formule
Cl2CHCO2Na
Poids formulaire
150.93
Point de fusion
197-199° dec.
Sensibilité
Moisture Sensitive
Solubilité
Soluble in water.

Applications

Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.

Notes

Moisture sensitive. Incompatible with strong oxidizing agents.

Références bibliographiques

Agnoletto, C.; Brunelli, L.; Melloni, E.; Pastorelli, R.; Casciano, F.; Rimondi, E.; Rigolin, G. M.; Cuneo, A.; Secchiero, P.; Zauli, G. The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway. Oncotarget 2015, 6 (4), 2385-2396.

Ji, B.; Tang, P.; Yan, K.; Sun, G. Catalytic actions of alkaline salts in reactions between 1, 2, 3, 4-butanetetracarboxylic acid and cellulose: II. Esterification. Carbohydr. Polym. 2015, 132, 228-236.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H341-H315-H319-H335-H303

Suspected of causing genetic defects. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Mentions de prudence: P201-P261-P280-P281-P305+P351+P338-P304+P340-P362-P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé
2915.40
TSCA
No

Recommandé

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Catalyseurs

Analytique et matériel de laboratoire