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2156-56-1 - Sodium dichloroacetate, 97% - Dichloroacetic acid sodium salt - B21827 - Alfa Aesar

B21827 Sodium dichloroacetate, 97%

Numéro CAS
2156-56-1
Synonymes
Dichloroacetic acid sodium salt

Dimensions Prix ($) Quantité Disponibilité
10g 60,60
50g 230,00
250g 844,00
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Sodium dichloroacetate, 97%

MDL
MFCD00070489
EINECS
218-461-3

Propriétés chimiques

Formule
Cl2CHCO2Na
Poids formulaire
150.93
Point de fusion
197-199° dec.
Sensibilité
Moisture Sensitive
Solubilité
Soluble in water.

Applications

Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.

Notes

Moisture sensitive. Incompatible with strong oxidizing agents.

Références bibliographiques

Agnoletto, C.; Brunelli, L.; Melloni, E.; Pastorelli, R.; Casciano, F.; Rimondi, E.; Rigolin, G. M.; Cuneo, A.; Secchiero, P.; Zauli, G. The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway. Oncotarget 2015, 6 (4), 2385-2396.

Ji, B.; Tang, P.; Yan, K.; Sun, G. Catalytic actions of alkaline salts in reactions between 1, 2, 3, 4-butanetetracarboxylic acid and cellulose: II. Esterification. Carbohydr. Polym. 2015, 132, 228-236.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H303-H315-H319-H341-H335

May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of causing genetic defects. May cause respiratory irritation.

Mentions de prudence: P201-P261-P280-P305+P351+P338-P304+P340-P312a-P308+P313-P405-P403+P233-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé
2915.40
TSCA
No

Recommandé

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Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire