1,2,4-tribromobenzene is used in the synthesis of hyper branched poly(p-phenylene ethynylenes). It is used as cross-linking reagent during Pd-catalyzed cross-coupling of 2,5-diiodo-4-[(2-ethylhexyl)oxy]methoxybenzene and 1,4-diethynyl-2,5-bis-(octyloxy)benzene. It is a compound commonly used in organic synthesis reactions.
Peter K. Freeman and Christian M. Haugen. Differential photohydrodehalogenation reactivity of bromobenzenes (1,2,4-tribromobenzene, 1,2,3,5-tetrabromobenzene) and pentachlorobenzene: Sunlight-based remediation.J. Chem. Technol. Biotechnol.,1998,72(1), 45-49.
Eric N. Smith, et al. Various pharmacokinetic parameters in relation to enzyme-inducing abilities of 1,2,4-trichlorobenzene and 1,2,4-tribromobenzene.Journal of Toxicology and Environmental Health.,1980,6(4), 737-749.
Mentions de danger (UE): H315-H319
Causes skin irritation. Causes serious eye irritation.
Mentions de prudence: P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313
Wear protective gloves and eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: