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298-83-9 - Nitro Blue Tetrazolium chloride, tech. 90% - Nitro BT - Nitrotetrazolium Blue chloride - B23792 - Alfa Aesar

B23792 Nitro Blue Tetrazolium chloride, tech. 90%

Numéro CAS
298-83-9
Synonymes
Nitro BT
Nitrotetrazolium Blue chloride

Dimensions Prix ($) Quantité Disponibilité
0.5g 81,90
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Nitro Blue Tetrazolium chloride, tech. 90%

MDL
MFCD00150013
EINECS
206-067-4

Propriétés chimiques

Formule
C40H30Cl2N10O6
Poids formulaire
817.65
Point de fusion
ca 190° dec.
Solubilité
Soluble in water, ethanol and methanol.

Applications

Nitro Blue Tetrazolium chloride is used to confirm diagnosis of chronic granulomatous disease. It is a microscopic stain, which is used to detect dehydrogenases and alkaline phosphatase. It acts as an NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase. Further, it is used in immunology for detection of alkaline phosphatase. In addition to this, it acts as an oxidant.

Notes

Light sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Références bibliographiques

Substrate for determination of various enzymes.

Materska, M.; Konopacka, M.; Rogoliński, J.; Ślosarek, K. Antioxidant activity and protective effects against oxidative damage of human cells induced by X-radiation of phenolic glycosides isolated from pepper fruits Capsicum annuum L. Food Chem. 2015, 168, 546-553.

Xiong, B.; Xu, R.; Zhou, R.; He, Y.; Yeung, E. S. Preventing UV induced cell damage by scavenging reactive oxygen species with enzyme-mimic Au-Pt nanocomposites. Talanta 2014, 120, 262-267.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
4115923
Code tarifaire harmonisé
2933.99
TSCA
Yes
RTECS
XF8045000

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Catalyseurs

Analytique et matériel de laboratoire