2-(Difluoromethoxy)benzaldehyde is an important raw material used as an intermediate in the preparation of pharmaceuticals, agrochemicals, and dyestuffs. It is also involved in the preparation of 4-(2-difluoromethoxyphenyl)- substituted 1,4-dihydropyridine 3,5-diesters.
Krauze, A.; Andzans, Z.; Krasnova, L.; Germane, S.; Domracheva, I.; Adlere, I.; Grinberga, S.; Duburs, G. Synthesis of 3-alkoxycarbonyl-6-alkylsulfanyl-4-[2-(difluoromethoxy)phenyl]-1,4-dihydropyridines and related derivatives as analogs of cognition enhancer cerebrocrast. Chem. Heterocycl. Compd. 2013, 49 (4), 566-573.
Andzans, Z.; Krauze, A.; Adlere, I.; Krasnova, L.; Duburs, G. Synthesis and enantioselective lipase-catalyzed kinetic resolution of methyl 6-(methoxycarbonyl-methyl)sulfanyl-1,4-dihydropyridine-3-carboxylates. Chem. Heterocycl. Compd. 2013, 49 (3), 421-427.
Mentions de danger (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Mentions de prudence: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.