It is a reactant for organocatalytic tandem three component reactions of aldehyde, alkyl vinyl ketone, and amide. It is also employed as a reactant for synthesis of selective angiotensin II AT2 receptor agonists with reduced CYP 450 inhibition, allosteric glucokinase activators, hydantoin derivatives with antiproliferative activity, thiohydantoins and P2X7 receptor antagonists.
Yukie Mori.; Yoshio Sakaguchi.; Hisaharu Hayashi. Magnetic field effects on the photoinduced electron transfer of 10-methylphenothiazine with 4-(4-cyanobenzoyloxy)TEMPO in fluid solutions. Chem. Phys. Lett. 1998, 286 (5-6),446-451 .
Kekeli Ekoue-Kovi.; Hanhui Xu.; Christian Wolf. Palladium-phosphinous acid-catalyzed cross-coupling of aliphatic and aromatic acyl chlorides with boronic acids. Tetrahedron Lett. 2008, 49 (40),5773-5776 .
Mentions de danger (UE): H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Mentions de prudence: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.