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66648-50-8 - Ethyl 3,4-dihydroxycinnamate, 97% - Ethyl caffeate - 3,4-Dihydroxycinnamic acid ethyl ester - B24808 - Alfa Aesar

B24808 Ethyl 3,4-dihydroxycinnamate, 97%

Numéro CAS
66648-50-8
Synonymes
Ethyl caffeate
3,4-Dihydroxycinnamic acid ethyl ester

Dimensions Prix ($) Quantité Disponibilité
1g 32,16
5g 135,96
25g 392,80
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Ethyl 3,4-dihydroxycinnamate, 97%

MDL
MFCD00045754

Propriétés chimiques

Formule
C11H12O4
Poids formulaire
208.22

Applications

Ethyl 3,4-dihydroxycinnamate shows anti-inflammatory, immunomodulatory, and anti-carcinogenic properties. It is a potent and specific inhibitor of NF-κB and its downstream inflammatory mediators: NOS2 (inducible nitric oxide synthase; NOS; NOS II), Cox-2 (cyclooxygenase-2), and prostaglandin E2 (PGE2). Ethyl 3,4-Dihydroxycinnamate prevents DNA single-strand breaks caused by H2O2.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible materials are oxidizing agents Store at -20°C.

Références bibliographiques

Yi-Ming Chiang; Chiu-Ping Lo; Yi-Ping Chen; Sheng-Yang Wang; Ning-Sun Yang; Yueh-Hsiung Kuo and Lie-Fen Shyur. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2in vitro or in mouse skin. British Journal of Pharmacology. 2003, 146, 352-363.

Meixian Xiang; Hanwen Su; Jinyue Hu and Yunjun Yan. Isolation, identification and determination of methyl caffeate, ethyl caffeate and other phenolic compounds from Polygonum amplexicaule var. sinense. Journal of Medicinal Plants Research. 2003, 5, (9), 1685-1691.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé
2918.29
TSCA
No

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Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire