2-Bromo-5-fluorobenzaldehyde is used as a precursor for the synthesis of 5-fluoro-3-substituted benzoxaboroles, which is used in material science as molecular receptors, building block in crystal engineering, as steroid conjugates for molecular imprinting , dyes and biosensors of alpha hydroxyl carboxylic acids. It is also used in the synthesis of 5-arylindazolo[3,2-b]quinazolin-7(5H)-one by reacting with 2-amino-N'-arylbenzohydrazide in the presence of Copper(I) bromide by the Ullmann-type reaction.
Sene, S.; Berthomieu, D.; Donnadieu, B.; Richeter, S.; Vezzani, J.; Granier, D.; Bégu, S.; Mutin, H.; Gervais, C.; Laurencin, D. A combined experimental-computational study of benzoxaborole crystal structures. Acta Crystallogr. Sect. E: Struct. Rep. Online 2013, 69 (8), 1246.
Mentions de danger (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Mentions de prudence: P261-P280a-P305+P351+P338-P304+P340-P405-P501a