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79651-64-2 - 2-Aminopyridine-6-methanol, 97% - 2-Amino-6-(hydroxymethyl)pyridine - H33485 - Alfa Aesar

H33485 2-Aminopyridine-6-methanol, 97%

Numéro CAS
79651-64-2
Synonymes
2-Amino-6-(hydroxymethyl)pyridine

Dimensions Prix ($) Quantité Disponibilité
250mg 57,12
1g 203,94
5g 528,80
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2-Aminopyridine-6-methanol, 97%

MDL
MFCD09863097

Propriétés chimiques

Formule
C6H8N2O
Poids formulaire
124.14
Point de fusion
87-92°
Solubilité
Slightly soluble.

Applications

4-Aminopyridine (4-AP), a well-known potassium channel blocker, has been shown to enhance conduction in injured and demyelinated axons. Aminopyridine has a narrow therapeutic range in clinical application. In the current study, we investigated whether AP-MeOH can enhance impulse conduction in an animal model of MS.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Références bibliographiques

Jinfeng Zhao,; Peng Song,; Yanling Cui,; Xuemei Liu,; Shaowu Sun,; Siyao Hou,; Fengcai Ma. Effects of hydrogen bond on 2-aminopyridine and its derivatives complexes in methanol solvent. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2015, 131 282-287.

Gary Leung,; Wenjing Sun,; Sarah Brookes,; Daniel Smith,; Riyi Shi. Potassium channel blocker, 4-aminopyridine-3-methanol, restores axonal conduction in spinal cord of an animal model of multiple sclerosis. Experimental Neurology. year of publication , 227 (1), 232-235.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé
2933.39
TSCA
No

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Consulté récemment

Produits chimiques

Sciences de la vie

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Catalyseurs

Analytique et matériel de laboratoire