H51156 Isopropylmagnesium chloride - LiCl complex, 1M in MeTHF
FDS
| Conditionnement | Prix ($) | Quantité | Disponibilité |
|---|---|---|---|
| 100ml | 86,20 |
|
|
| 500ml | 358,00 |
|
|
Isopropylmagnesium chloride - LiCl complex, 1M in MeTHF
Propriétés chimiques
Applications
Isopropylmagnesium chloride is used in the regioselective functionalization of trisubstituted pyridines, electrophilic amination for preparation of amines and functionalization of cyclopentene derivatives. It is involved in the preparation of 2,3-functionalized furans, benzofurans, and thiophenes. Further, it is used in benzylic Grignards via sulfur-magnesium exchange.
Notes
Références bibliographiques
Huddleston, N. E.; Roy, A.; Bilbrey, J. A.; Zhao, Y.; Locklin, J. Functionalization of Reactive End Groups in Surface-Initiated Kumada Catalyst-Transfer Polycondensation. Macromol. Symp. 2015, 351 (1), 27-36.
Hickey, M. J.; Kingston, L. P.; Allen, P. H.; Johnson, T.; Wilkinson, D. J. A short expedient synthesis of [14C]Ticlopidine. J. Labelled Compd. Radiopharm. 2014, 57 (3), 172-174.
Mentions de danger et de prudence du SGH
Mentions de danger (UE): H225-H261-H314-H318
Highly flammable liquid and vapour. In contact with water releases flammable gas. Causes severe skin burns and eye damage. Causes serious eye damage.
Mentions de prudence: P223-P210-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from any possible contact with water, because of violent reaction and possible flash fire. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
