4-Benzoyl-L-phenylalanine is a photoreactive amino acid which can easily be incorporated into a peptide by solid-phase synthesis and finds application as phtolabel. It is an important raw material as well as an intermediate in organic synthesis.
Pradhan, D.; Priyadarshini, V.; Munikumar, M.; Swargam, S.; Umamaheswari, A.; Bitla, A. Para-(benzoyl)-phenylalanine as a potential inhibitor against LpxC of Leptospira spp.: homology modeling, docking, and molecular dynamics study. J. Biomol. Struct. Dyn. 2014, 32 (2), 171-185.
Liu, W.; Alfonta, L.; Mack, A. V.; Schultz, P. G. Structural Basis for the Recognition of para-Benzoyl-L-phenylalanine by Evolved Aminoacyl-tRNA Synthetases. Angew. Chem. Int. Ed. 2007, 46 (32), 6073-6075.
Dorman, G.; Olszewski, J. D.; Prestwich, G. D.; Hong, Y.; Ahern, D. G. Synthesis of Highly Tritiated 4-Benzoyl-L-phenylalanine, a Photoactivatable Amino Acid. J. Org. Chem. 1995, 60 (7), 2292-2297.
Mentions de prudence: P260-P201-P280-P304+P340-P405-P501a
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