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H54449 4,6-Dichloropyrimidine-5-carboxaldehyde, 97%

Numéro de CAS
5305-40-8
Synonymes

Stock No. Conditionnement Prix ($) Quantité Disponibilité
H54449-03 1g 32,10
H54449-06 5g 119,00
H54449-14 25g 476,00
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4,6-Dichloropyrimidine-5-carboxaldehyde, 97%

MDL
MFCD02257701

Propriétés chimiques

Formule
C5H2Cl2N2O
Poids moleculaire
175.99
Point de fusion
66-71°
Storage & Sensitivity
Keep Cold.

Applications

4,6-Dichloropyrimidine-5-carboxaldehyde is used as a substrate in the synthesis of N-terminal surrogate in amino acid and peptide analogues.

Notes

Incompatible with strong oxidizing agents and strong acids. Store in cool place.

Références bibliographiques

Li, B.; Yue, Z.; Xiang, H.; Lv, L.; Song, S.; Miao, Z.; Yang, C. Catalyst-free synthesis of benzofuran-fused pyrido[4,3-d]pyrimidines from 2-(2-hydroxyaryl)acetonitrile and 4,6-dichloropyrimidine-5-carbaldehyde through domino condensation reactions. RCS Adv. 2015, 4 (1), 358-364.

Schenone, S.; Radi, M.; Musumeci, F.; Brullo, C.; Botta, M. Biologically Driven Synthesis of Pyrazolo[3,4-d]pyrimidines As Protein Kinase Inhibitors: An Old Scaffold As a New Tool for Medicinal Chemistry and Chemical Biology Studies. Chem. Rev. 2014, 114 (14), 7189-7238.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Autres références

Code tarifaire harmonisé
2933.59
TSCA
No

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Consulté récemment

Produits chimiques

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Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire