2-Methyl-4(5)-nitroimidazole was used to study the mechanism of both the alkaline and acidic hydrolysis of tinidazole. It is mainly used to synthesize intermediate of medicines such as Metronidazole and dimetridazole.
Jukka-Pekka K Salo; Jari Yli-Kauhaluoma; Hannele Salomies. On the hydrolytic behavior of tinidazole, metronidazole, and ornidazole. Journal of Pharmaceutical Sciences. 2003, 92 (4), 739-746.
Y Henry; A Guissani, B Hickel. Radicals of nitroimidazole derivatives: pH dependence of rates of formation and decay related to acid-base equilibria. International journal of radiation biology and related studies in physics, chemistry, and medicine. 1987, 51 (5), 797-809.
Mentions de danger (UE): H302
Harmful if swallowed.
Mentions de prudence: P260-P201-P280-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.