2,2,3,3-Tetramethylcyclopropanecarboxylic acid is used to start synthesis of central nervous system-active compounds.
Eyal Sobol.; Meir Bialer.; Boris Yagen. Tetramethylcyclopropyl Analogue of a Leading Antiepileptic Drug, Valproic Acid. Synthesis and Evaluation of Anticonvulsant Activity of Its Amide Derivatives. J. Med. Chem. 2004, 47 (17), 4316-4326.
Neta Pessah.; Meir Bialer.; Bogdan Wlodarczyk.; Richard H. Finnell.; Boris Yagen. α-Fluoro-2,2,3,3-Tetramethylcyclopropanecarboxamide, a Novel Potent Anticonvulsant Derivative of a Cyclic Analogue of Valproic Acid. J. Med. Chem. 2009, 52 (8), 2233-2242.
Mentions de danger (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Mentions de prudence: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.