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2075-45-8 - 4-Bromo-1H-pyrazole, 98+% - H64673 - Alfa Aesar

H64673 4-Bromo-1H-pyrazole, 98+%

Numéro de CAS
2075-45-8
Synonymes

Conditionnement Prix ($) Quantité Disponibilité
25g 31,80
500g 269,00
1kg 449,00
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4-Bromo-1H-pyrazole, 98+%

MDL
MFCD00075602

Propriétés chimiques

Formule
C3H3BrN2
Poids moleculaire
146.97
Point de fusion
93-96° lit.
Point d'ébullition
250-260° lit.
Solubilité
Slightly soluble in water.

Applications

4-Bromopyrazole may be used in the preparation of 4-bromo-1-(2-chloroethyl)-1H-pyrazole. It may be used as starting material in the synthesis of 1,4?-bipyrazoles. Also used in the synthesis of various pharmaceutical and biologically active compounds, including inhibitors. It is also shown to be one of the 4-substituted pyrazoles, being able to act as inhibitor of liver alcohol dehydrogenase.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

Références bibliographiques

Guzei IA; and Winter CH. Structural Diversity in the Reaction of Mono- and Disubstituted Pyrazoles with Titanium Tetrachloride. Importance of Hydrogen Bonding and Trends in cis/trans Geometry of Binary Adducts with Unidentate Ligands. Inorg. Chem. 1997 36(20), 4415-4420.

E Alejandre-Durán; M Ruiz-Rubio; R M Claramunt; C López; C Pueyo. Mutagenicity study on pyrazole, seven pyrazole derivatives, and two nitroimidazoles with the L-arabinose resistance test of Salmonella typhimurium. Environmental Mutagenesis.1986 8(4), 611-619.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
106510
Code tarifaire harmonisé
2933.19
TSCA
No
RTECS
UQ6200000

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Consulté récemment

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Catalyseurs

Analytique et matériel de laboratoire