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65-19-0 - Yohimbine hydrochloride, 98+% - 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride - J60185 - Alfa Aesar

J60185 Yohimbine hydrochloride, 98+%

Numéro CAS
65-19-0
Synonymes
17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride

Dimensions Prix ($) Quantité Disponibilité
1g 40,77
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Yohimbine hydrochloride, 98+%

MDL
MFCD00012674
EINECS
200-600-4

Propriétés chimiques

Formule
C21H26N2O3•HCl
Poids formulaire
390.91
Forme
Powder
Point de fusion
288-290°
Sensibilité
Light Sensitive
Solubilité
Soluble in dimethyl sulfoxide and methanol.

Applications

Yohimbine hydrochloride is an α2-adrenergic receptor antagonist. It blocks the central α2-adrenegic receptors in the brain, thus preventing and reducing the effects of xylazine, an α2-adrenergic agonist. The sedative effects and respiratory depression that accompany xylazine administration are both antagonized and reversed by yohimbine. Yohimbine hydrochloride also produces an antidiuretic effect, and increases heart rate and blood pressure.

Notes

Light Sensitive, store in dark. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Références bibliographiques

W Zhang and G M Roomans. A yohimbine-dependent, UK14,304 induced ion transient in HT29 cells studied by X-ray microanalysis. Scanning microscopy, 1996, 10(1), 293-299.

Susan X. Jiang et. al. Reversible inhibition of intracellular calcium influx through NMDA receptors by imidazoline I2receptor antagonists. European Journal of Pharmacology, 2010,629,(1), 12-19.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H300-H310-H330

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.

Mentions de prudence: P260-P284-P301+P310-P304+P340-P320-P330-P361-P302+P350-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Remove/Take off immediately all contaminated clothing. IF ON SKIN: Gently wash with plenty of soap and water. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,10102
Classe de danger
6.1
Groupe d'emballage
II
Code tarifaire harmonisé
2939.99
TSCA
Yes
RTECS
ZG1015000

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Analytique et matériel de laboratoire