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13957-31-8 - 4-Thiouridine, 98+% - J60679 - Alfa Aesar

J60679 4-Thiouridine, 98+%

Numéro CAS

Dimensions Prix ($) Quantité Disponibilité
100mg 393,00
250mg 575,00
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4-Thiouridine, 98+%


Propriétés chimiques

Poids formulaire
Soluble in water (20 mg/ml), and methanol (10 mg/ml).


4-Thiouridine is a constituent of several transfer RNA's. 4-Thiouridine is a thionucleobase used as an antisense agent. Widely used for RNA analysis including RNA-RNA cross coupling and RNA labelling. 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. 4-Thio Uridine is typically used to modify oligos slated for RNA, or RNA-protein, structural studies. A 4-thio-rU modified RNA pentamer was used to study the effect of this modification on codon-anticodon interaction when it is in the wobble position of tRNA.


Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Références bibliographiques

A. Favre,; M. Yaniv,; A.M. Michels.The photochemistry of 4-thiouridine in escherichia coli t-RNAİVal. Biochemical and Biophysical Research Communications. 1969, 37 (2), 266-271.

L. Aravind,; Eugene V. Koonin.THUMP - a predicted RNA-binding domain shared by 4-thiouridine, pseudouridine synthases and RNA methylases. Trends in biochemical science. 2001, 26 (4) ,215-217.

Mentions de danger et de prudence du SGH

Mentions de prudence: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé


Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux


Analytique et matériel de laboratoire