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130-61-0 - Thioridazine hydrochloride - J60895 - Alfa Aesar

J60895 Thioridazine hydrochloride

Numéro CAS
130-61-0
Synonymes

Dimensions Prix ($) Quantité Disponibilité
5g 58,50
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Thioridazine hydrochloride

MDL
MFCD00012655
EINECS
204-992-8

Propriétés chimiques

Formule
C21H26N2S2•HCl
Poids formulaire
407.03
Forme
Powder
Point de fusion
161-163°
Sensibilité
Light Sensitive & Hygroscopic
Solubilité
Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.

Applications

Thioridazine is a piperidine typical antipsychotic drug belonging to the phenothiazine widely used in the treatment of schizophrenia and psychosis. It primary use in medicine was the treatment of schizophrenia.This medication is used to treat certain mental/mood disorders (e.g., schizophrenia). Thioridazine·HCl is a calcium channel protein inhibitor as well as a D2DR/D4DR inhibitor. It is an intercalating agent for analyzing the integrity of double stranded DNA by using the square-wave voltammetry.

Notes

Light Sensitive & Hygroscopic. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light, water, moisture.

Références bibliographiques

H. Garfield Kelly,; J. E. Fay,; S. G. Laverty.Thioridazine Hydrochloride (Mellaril): Its Effect on the Electrocardiogram and a Report of Two Fatalities with Electrocardiographic Abnormalities. Can Med Assoc J. 1963, 89 (11), 546-554.

John R. Huston, MD; George E. Bell, MD.The Effect of Thioridazine Hydrochloride and Chlorpromazine on the Electrocardiogram. JAMA. 1966, 198 (1), 16-20..

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H400-H410-H302-H315-H319-H335

Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P273-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,9359
Classe de danger
9
Groupe d'emballage
III
Code tarifaire harmonisé
2934.30
TSCA
No
RTECS
SP2275000

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