Consentement d'utilisation des Cookies

J'accepte. Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

J61071 Castanospermine, 99%

Numéro de CAS
79831-76-8
Synonymes
(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine

Stock No. Conditionnement Prix ($) Quantité Disponibilité
J61071-MC 100mg 200,00
J61071-ME 500mg 707,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Castanospermine, 99%

MDL
MFCD00017555

Propriétés chimiques

Formule
C8H15NO4
Poids moleculaire
189.21
Forme
Solid
Point de fusion
213-217°
Storage & Sensitivity
Keep Cold.
Solubilité
Soluble in water

Applications

Castanospermine, is used as a glycosidase inhibitor and antiinflammatory agent.castanospermine is used to inhibit syncytium formation between HIV-infected and CD4-expressing cells and may also interfere with infectivity. It has also been demonstrated that this agent inhibits inflammation at the level of leukocyte extravasation in rat models of experimental adjuvant-induced arthritis and autoimmune encephalomyelitis. Castanospermine is an inhibitor of Glucosidase I, Maltase-glucoamylase, and MANBA. Potent inhibitor of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.

Références bibliographiques

Saul et al. Studies on the mechanism of castanospermine inhibition of α- and β-glucosidases. Arch.Biochem.Biophys. 1984, 230,(2), 668-75.

Gruters et al. Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase. Nature. 1987, 330,(6143), 74-7.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H312-H332

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

Mentions de prudence: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P312-P330-P363-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Rinse mouth. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Autres références

Merck
14,1896
Beilstein
3588654
Code tarifaire harmonisé
2933.99
TSCA
No

Recommandé

  • B22425

    3-Chloro-4-fluoroanisole, 97%
  • H56307

    (R)-(-)-3-Hydroxytetrahydrofuran, 98%
  • H34474

    N-(4'-Chloro-4-biphenylylsulfonyl)-DL-valine, 96%
  • H54109

    (Boc-aminooxy)acetic acid, 98+%
  • J66980

    Tumor Necrosis Factor-alpha (46-65), human

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire