Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

104594-70-9 - Phenylethyl 3,4-dihydroxycinnamate, 99+% - 3,4-Dihydroxycinnamic acid phenylethyl ester - Phenylethyl caffeate - J61386 - Alfa Aesar

J61386 Phenylethyl 3,4-dihydroxycinnamate, 99+%

Numéro CAS
104594-70-9
Synonymes
3,4-Dihydroxycinnamic acid phenylethyl ester
Phenylethyl caffeate

Dimensions Prix ($) Quantité Disponibilité
250mg 125,00
1g 372,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Phenylethyl 3,4-dihydroxycinnamate, 99+%

MDL
MFCD00866470

Propriétés chimiques

Formule
C17H16O4
Poids formulaire
284.31
Forme
Crystalline powder
Point de fusion
127-129°
Sensibilité
Light Sensitive
Solubilité
Soluble in ethyl acetate at 50mg/ml. Soluble in DMSO and ethanol.

Applications

Phenylethyl 3,4-dihydroxycinnamate is a potent and specific inhibitor of nuclear transcription factor, NF-κB, activation. It has been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation. It inhibits HIV-1 integrase and also inhibits proliferation of transformed cells. It induces apoptosis in transformed fibroblasts, and interferes with EGF signal transduction affecting both protein kinase C and ornithine decarboxylase activity.

Notes

Light sensitive. Incompatible with oxidizing agents and heat.

Références bibliographiques

M.R.Fesen; Y.Pommier; F.Leteurtre; S.Hiroguchi; J.Yung; K.W.Kohn; Mark R.Fesen; Yves Pommier; Francois Leteurtre; Satoshi Hiroguchi; Jessie Yung; Kurt W.Kohn. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochemical Pharmacology. 1994, 48,(3), 595-608.

 

Z.S.Zheng; G.Z.Xue; D.Grunberger; J.H.Prystowsky. Caffeic acid phenethyl ester inhibits proliferation of human keratinocytes and interferes with the EGF regulation of ornithine decarboxylase. Oncology Research. 1995, 7,(9), 445-452.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé
2918.29
TSCA
No
RTECS
UD3334375

Recommandé

  • J67544

    Tris-glycine-SDS large precast gel, 2D, 10%, 20x20cm, 22.3x20cm (back) low fluor., 1 well, for Bio-Rad® systems
  • 40387

    Cobalt naphthenate, Co 6%, approximately 53% in mineral spirits
  • B25650

    2,5-Dichlorobenzenesulfonic acid dihydrate, 97%
  • H63438

    1-Boc-4-(4-Fluoro-2-nitrophenyl)piperazine, 97%
  • H32609

    5-Amino-4-bromo-3-methyl-1-phenyl-1H-pyrazole, 97%

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire