In cell culture, polymyxin B sulfate is used as an antibacterial agent to prevent contamination. Polymyxin B sulfate is recommended for use in cell culture applications at 50 mg/L. It is used as a lipid A binding agent that induces pore formation in cell membranes and as immobilized (substrate bound) agent for removal of endotoxins.
RD Leunk.; PT Johnson.; BC David. Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J. Med. Microbiol. < span>1988, 26, (2), 93-99.
JB Weinberg, HA Chapman. Characterization of the effects of endotoxin on macrophage tumor cell killing. The Journal of Immunology. < span>1978, 121, (1), 72-80.
Mentions de danger (UE): H302-H336
Harmful if swallowed. May cause drowsiness or dizziness.
Mentions de prudence: P261-P264b-P270-P271-P301+P312-P304+P340-P312-P330-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant