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24280-93-1 - Mycophenolic acid, 98% - J61905 - Alfa Aesar

J61905 Mycophenolic acid, 98%

Numéro CAS
24280-93-1
Synonymes

Dimensions Prix ($) Quantité Disponibilité
1g 34,70
5g 98,30
10g 171,00
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Mycophenolic acid, 98%

MDL
MFCD00036814
EINECS
246-119-3

Propriétés chimiques

Formule
C17H20O6
Poids formulaire
320.34
Forme
Powder
Point de fusion
139-141°
Solubilité
Soluble in methanol at 50mg/ml

Applications

It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly inhibits proliferation of T and B lymphocytes and antibody formation.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agent.

Références bibliographiques

Eugui et al. Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depeletion. Scand.J.Immunol. 1991, 33, (2), 161-73.

Allison et al. Mechanisms of action of mycophenolic acid. Ann.N.Y.Acad.Sci. 1993, 696, 63-87.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302

Harmful if swallowed.

Mentions de prudence: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,6327
Beilstein
1295848
Code tarifaire harmonisé
2941.90
TSCA
No
RTECS
MP8050000

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Catalyseurs

Analytique et matériel de laboratoire