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70-18-8 - L-Glutathione, reduced, 98+% - gamma-L-Glutamyl-L-cysteinylglycine - GSH - J62166 - Alfa Aesar

J62166 L-Glutathione, reduced, 98+%

Numéro de CAS
70-18-8
Synonymes
gamma-L-Glutamyl-L-cysteinylglycine
GSH

Conditionnement Prix ($) Quantité Disponibilité
5g 37,70
25g 89,80
100g 239,00
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L-Glutathione, reduced, 98+%

MDL
MFCD00065939
EINECS
200-725-4

Propriétés chimiques

Formule
C10H17N3O6S
Poids moleculaire
307.33
Forme
Crystalline powder
Point de fusion
ca 193° dec.
Solubilité
Soluble in water, dimethyl formamide, ethanol, phosphate buffered saline, diluted alcohol, liquid ammonia and dimethyl sulfoxide.

Applications

A tripeptide used for the reductive cleavage of disulfide bonds L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.

Notes

Store in cool place. Incompatible with strong oxidizing agents.

Références bibliographiques

Deheshi, S.; Dabiri, B.; Fan, S.; Tsang, M.; Rintoul, G. L. Changes in mitochondrial morphology induced by calcium or rotenone in primary astrocytes occur predominantly through ros-mediated remodeling. J. Neurochem. 2015, 133 (5), 684-699.

Li, X.; Zheng, L.; Wang, Y.; Zhang, N.; Lou, Y.; Xiao, T.; Liu, J. A novel electrocatalyst with high sensitivity in detecting glutathione reduced by 2-hydroxypropyl- β-cyclodextrin enveloped 10-methylphenothiazine. RSC Adv. 2015, 5 (88), 71749-71755.

Mentions de danger et de prudence du SGH

Mentions de prudence: P260-P201-P280-P304+P340-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,4475
Beilstein
1729812
Code tarifaire harmonisé
2930.90
TSCA
Yes
RTECS
MC0556000

Recommandé

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Sciences de la vie

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Catalyseurs

Analytique et matériel de laboratoire