Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

11089-65-9 - Tunicamycin, 95% - J62217 - Alfa Aesar

J62217 Tunicamycin, 95%

Numéro CAS
11089-65-9
Synonymes

Dimensions Prix ($) Quantité Disponibilité
10mg 171,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Tunicamycin, 95%

MDL
MFCD00065709

Propriétés chimiques

Formule
C39H64N4O16
Poids formulaire
844.95
Forme
Powder
Sensibilité
Moisture & Light Sensitive
Solubilité
Soluble in methanol, ethanol, DMSO, or DMF

Applications

Tunicamycin has been widely used in the study of glycoprotein synthesis in various biological systems. During protein glycosylation, tunicamycin is noted to be an inhibitor of the transfer of saccharide moieties to dolichol during dolichol-linked glycoprotein synthesis. Dose-dependent inhibition of DNA synthesis may be related to the alteration of glycoproteins, which thereby affects the transport of thymidine into cells. Additionally, tunicamycin has been reported to prevent cell cycle progression in primary cultures of rat glial cells, as well as inhibit lipid-mediated protein glycosylation in chick or mouse fibroblasts in a dose-dependent manner.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C Light sensitive. Moisture sensitive.

Références bibliographiques

Ding et al. Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J.Biol.Chem. 2007, 282, (7), 4702-10.

Duriez et al. The hepatitis B virus precore protein is retrotransported from endoplasmic reticulum (ER) to cytosol through the ER-associated pathway. J.Biol.Chem. 2008, 283, (47), 32352-60.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H300-H330-H373

Fatal if swallowed. Fatal if inhaled. May cause damage to organs through prolonged or repeated exposure.

Mentions de prudence: P260-P284-P301+P310-P304+P340-P320-P330-P310-P405-P403+P233-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,9819
Beilstein
6888090
Classe de danger
6.1
Groupe d'emballage
II
Code tarifaire harmonisé
2941.90
TSCA
No
RTECS
YO7980200

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire