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J62324 Veratridine, 97+%

Numéro de CAS
71-62-5
Synonymes
3-Veratroylveracevine

Stock No. Conditionnement Prix ($) Quantité Disponibilité
J62324-MF 50mg 532,00
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Veratridine, 97+%

MDL
MFCD00082515
EINECS
200-758-4

Propriétés chimiques

Formule
C36H51NO11
Poids moleculaire
673.80
Forme
Powder
Storage & Sensitivity
Store at -20°C.
Solubilité
Soluble in ethanol or DMSO. Freely soluble in chloroform. Also soluble in 1M HCl

Applications

Veratridine causes Na+ channels to stay open during a sustained membrane depolarization by abolishing inactivation. This, in turn, opens voltage-activated calcium channels, thus increasing intracellular calcium content and inducing neurotransmitter release. Alkaloid neurotoxin which depolarizes excitable tissue; used to increase membrane sodium permeability.

Notes

Store at -20°C. Incompatible with oxidizing agents. Protect from heat.

Références bibliographiques

Stephen R. Skilling.; David H. Smullin.; Alvin J. Beitz.; Alice A. Larson. Extracellular Amino Acid Concentrations in the Dorsal Spinal Cord of Freely Moving Rats Following Veratridine and Nociceptive Stimulation.J. Neurochem. 1988, 51 (1),127-132 .

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H300-H310-H315-H319-H330-H335

Fatal if swallowed. Fatal in contact with skin. Causes skin irritation. Causes serious eye irritation. Fatal if inhaled. May cause respiratory irritation.

Mentions de prudence: P260-P262-P264b-P270-P271-P280-P284-P301+P310-P302+P350-P304+P340-P305+P351+P338-P310-P312-P330-P332+P313-P337+P313-P361-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Do not get in eyes, on skin, or on clothing. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Gently wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Autres références

Merck
14,9954
Beilstein
78875
Classe de danger
6.1
Groupe d'emballage
I
Code tarifaire harmonisé
2939.80
TSCA
No
RTECS
YX5600000

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