Camptothecin is used as a cytotoxic antitumor agent that inhibits topoisomerase I.Camptothecin shows remarkable anticancer activity based on preliminary clinical trials. Its analogues are used in cancer chemotherapy. Cyclodextrin-based polymer containing camptothecin is used in the investigational anti-cancer drug study.
Li, R.; Shu, C.; Wang, W.; Wang, X.; Li, H.; Xu, D.; Zhong, W. Encapsulation of 10-Hydroxy Camptothecin in Supramolecular Hydrogel as an Injectable Drug Delivery System. J. Pharm. Sci. 2015, 104 (7), 2266-2275.
Liu, Y. Q.; Li, W. Q.; Natschke, S. L. M.; Qian, K.; Yang, L.; Zhu, G. X.; Wu, X. B.; Chen, A. L.; Zhang, S. Y.; Nan, X.; Lee, K. H. Perspectives on Biologically Active Camptothecin Derivatives. Med Res Rev 2015, 35 (4), 753-789.
Mentions de danger (UE): H301-H500
Toxic if swallowed. May form combustible dust concentrations in air
Mentions de prudence: P264b-P270-P301+P310-P330-P501c
Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant