Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

298-46-4 - Carbamazepine, 98% - 5H-Dibenz[b,f]azepine-5-carboxamide - J62590 - Alfa Aesar

J62590 Carbamazepine, 98%

Numéro CAS
298-46-4
Synonymes
5H-Dibenz[b,f]azepine-5-carboxamide

Dimensions Prix ($) Quantité Disponibilité
25g 95,00
100g 289,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Carbamazepine, 98%

MDL
MFCD00005073
EINECS
206-062-7

Propriétés chimiques

Formule
C15H12N2O
Poids formulaire
236.27
Forme
Powder
Point de fusion
189-192°
Solubilité
Soluble in ethanol, acetone, propylene glycol, chloroform, dimethyl sulfoxide, methanol, dimethyl fluoride,ethylene glycol and monoethyl ether. Slightly soluble in glacial acetic acid. Insoluble in water.

Applications

Carbamazepine is used as cytochrome P450 3A4 inducing anti-epileptic drug and ligand for the GABA-A receptor benzodiazepine modulatory site. Carbamazepine is typically used for the treatment of seizure disorders and neuropathic pain. It is associated with other medications and used to treat schizophrenia as well as a second line agent in bipolar disorders.

Notes

Store in cool place. Incompatible with strong oxidizing agents.

Références bibliographiques

Tolbert, D.; Cloyd, J.; Biton, V.; Bekersky, I.; Walzer, M.; Wesche, D.; Drummond, R.; Lee, D. Bioequivalence of oral and intravenous carbamazepine formulations in adult patients with epilepsy. Epilepsia. 2015, 56 (6), 915-923.

Shokry, E.; Villanelli, F.; Malvagia, S.; Rosati, A.; Forni, G.; Funghini, S.; Ombrone, D.; Bona, M. D.; Guerrini, R.; Marca, G. L. Therapeutic drug monitoring of carbamazepine and its metabolite in children from dried blood spots using liquid chromatography and tandem mass spectrometry. J. Pharm. Biomed. Anal. 2015, 109, 164-170.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H334-H317-H302

May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. Harmful if swallowed.

Mentions de prudence: P285-P261-P280-P342+P311-P301+P312-P363-P304+P341-P321-P333+P313-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,1781
Code tarifaire harmonisé
2933.99
TSCA
No
RTECS
HN8225000

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire