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139481-59-7 - Candesartan, 98% - J62818 - Alfa Aesar

J62818 Candesartan, 98%

Numéro CAS

Dimensions Prix ($) Quantité Disponibilité
100mg 53,90
1g 245,00
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Candesartan, 98%


Propriétés chimiques

Poids formulaire
Point de fusion
Soluble in ethyl acetate, methanol, water (<1 mg/ml at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C).


Candesartan is a selective AT1 (angiotensin II receptor 1) antagonist. Antagonism of angiotensin receptors inhibits vasoconstriction and the production of aldosterone, leading to a decrease in water and sodium concentration in blood plasma. Exhibits antihypertensive effects in animal models. Used in treatment of congestive heart failure, as antihypertensive. Candesartan does not affect cell viability or proliferation but increases the expression of VEGF and interleukin-8 in the cultured medium of KU-19-19 cells. Candesartan (0.1 nM) could reduce the maximal contractile response to angiostensin II by approximately 50%.


Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Références bibliographiques

Kaur N, et al. Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists.Bioorg Med Chem.,2008,16(24), 10210-5.

Nishikawa K, et al. Candesartan cilexetil: a review of its preclinical pharmacology.J Hum Hypertens.,1997,29-17.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H312-H332-H315-H319-H335

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P301+P312a-P321-P332+P313-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF SWALLOWED: Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé


  • L19899

    4'-Fluoro-3'-nitroacetophenone, 98%
  • 45927

    Dysprosium sputtering target, 76.2mm dia x 3.18mm thick
  • H31710

    2-(3,4-Difluorophenyl)ethanol, 97%
  • 13650

    Yttrium(III) fluoride, anhydrous, REacton®, 99.9% (REO)
  • 89485

    Bismuth(III) chloride, anhydrous, 99.999% (metals basis)

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