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10236-47-2 - Naringin - 4',5,7-Trihydroxyflavanone 7-rhamnoglucoside - J63166 - Alfa Aesar

J63166 Naringin

Numéro de CAS
10236-47-2
Synonymes
4',5,7-Trihydroxyflavanone 7-rhamnoglucoside

Conditionnement Prix ($) Quantité Disponibilité
25g 31,50
100g 112,00
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Naringin

MDL
MFCD00148888
EINECS
233-566-4

Propriétés chimiques

Formule
C27H32O14
Poids moleculaire
580.53
Forme
Powder
Solubilité
Soluble in water, alcohol, acetone and warm acetic acid.

Applications

A citrus bioflavanoid that inhibits cytochrome P-450 monooxygenase activityNaringin is used to prepare naringin dihydrochalcone, which is about 300-1800 times sweeter than sugar. It is a citrus bioflavonoid reported to inhibit cytochrome P450 monooxygenase activity. It also acts as an inhibitor of cytochrome P450 enzymes. It is employed as an antioxidant, lipid lowering and anticancer agent. In addition to this, it is used in a study to assess aldosterone production by a human adrenocortical cell line and to improve cognitive deficits of Alzheimer's disease.

Notes

Incompatible with strong oxidizing agents.

Références bibliographiques

Nguyen, M. A.; Staubach, P.; Tamai, I.; Langguth, P. High-dose short-term administration of naringin did not alter talinolol pharmacokinetics in humans. Eur. J. Pharm. Sci. 2015, 68, 36-42.

Pai, D. A.; Vangala, V. R.; Ng, J. W.; Ng, W. K.; Tan, R. B. H. Resistant maltodextrin as a shell material for encapsulation of naringin: Production and physicochemical characterization. J. Food Eng. 2015, 161, 68-74.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,6425
Beilstein
102012
Code tarifaire harmonisé
2938.90
TSCA
Yes
RTECS
QN6340000

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Consulté récemment

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Analytique et matériel de laboratoire