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24169-02-6 - Econazole nitrate - Ecostatin - 1-[2-(4-Chlorophenylmethoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate - J63173 - Alfa Aesar

J63173 Econazole nitrate

Numéro CAS
24169-02-6
Synonymes
Ecostatin
1-[2-(4-Chlorophenylmethoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate

Dimensions Prix ($) Quantité Disponibilité
5g 49,95
25g 201,60
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Econazole nitrate

MDL
MFCD00058160
EINECS
246-053-5

Propriétés chimiques

Formule
C18H15Cl3N2O•HNO3
Poids formulaire
444.70
Forme
Powder
Point de fusion
158-163°
Solubilité
Soluble at 0.4mg/ml in DMSO. Sparingly soluble in water.

Applications

Econazole nitrate is an antifungal medication often used as a cream to treat skin infections like tinea, ringworm and athlete's foot, personal care, cosmetic and pharmaceutical applications. It is used for studies on processes such as platelet serotonin uptake, prostanoid biosynthesis, EDHF-mediated relaxation, and Ca2+ transport pathways in thymic lymphocytes.

Notes

Keep container tightly closed. Store away from oxidizing agents. Store in cool, dry conditions in well sealed containers.

Références bibliographiques

Poonam Verma.; Kamla Pathak. Nanosized ethanolic vesicles loaded with econazole nitrate for the treatment of deep fungal infections through topical gel formulation. Nanomedicine: Nanotechnology, Biology and Medicine. 2012, 8, (4), 489-496.

Vanna Sanna.; Giuseppe Caria.; Alberto Mariani. Effect of lipid nanoparticles containing fatty alcohols having different chain length on the ex vivo skin permeability of Econazole nitrate. Powder Technology. 2010, 201, (1), 32-36.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H315-H319

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Mentions de prudence: P280-P264-P270-P305+P351+P338-P362-P301+P312-P321-P332+P313-P337+P313-P501a

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,3502
Code tarifaire harmonisé
2933.29
TSCA
No
RTECS
NI4450000

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Catalyseurs

Analytique et matériel de laboratoire