Non-selective cyclooxygenase inhibitorIndomethacin acts as an antiinflammatory, antipyretic and analgesic. It serves as an inhibitor cyclooxygenase such as Cox-1 and Cox-2. In addition to this, it is used as a prescription medication in order to reduce fever, stiffness, swelling and pain.
Tajiri, T.; Morita, S.; Sakamoto, R.; Mimura, H.; Ozaki, Y.; Reppas, C.; Kitamura, S. Developing dissolution testing methodologies for extended-release oral dosage forms with supersaturating properties. Case example: Solid dispersion matrix of indomethacin. Int. J. Pharm. 2015, 490 (1-2), 368-374.
Thakral, S.; Suryanarayanan, R. Salt formation during freeze-drying - an approach to enhance indomethacin dissolution. Pharm. Res. 2015, 32 (11), 3722-3731.
Mentions de danger (UE): H300-H341
Fatal if swallowed. Suspected of causing genetic defects.
Mentions de prudence: P260-P201-P280-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.