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58-32-2 - Dipyridamole - J63329 - Alfa Aesar

J63329 Dipyridamole

Numéro CAS
58-32-2
Synonymes

Dimensions Prix ($) Quantité Disponibilité
5g 41,20
25g 125,66
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Dipyridamole

MDL
MFCD00010555
EINECS
200-374-7

Propriétés chimiques

Formule
C24H40N8O4
Poids formulaire
504.63
Forme
Powder
Point de fusion
165-167°
Solubilité
Soluble in chloroform, methanol, dilute acids, ethanol. Slightly soluble in water.

Applications

Dipyridamole prevents platelets sticking to the replacement heart valve and causing a blood clot on the valve. It is used to dilate blood vessels in people with peripheral arterial disease and coronary artery disease. This compound has been shown to suppress high glucose-induced osteopontin mRNA expression and protein secretion, as well as inhibit cAMP and cGMP hydrolysis. Research indicates that Dipyridamole is a non-specific nucleoside transport inhibitor with the ability to increase the effects of adenosine in sinoatrial and atrioventricular nodes. Dipyridamole is an inhibitor of ENT1 and ENT2.

Notes

Store in a cool dry place. Keep away from oxidizing agents.

Références bibliographiques

H.C. Diener.; L. Cunha.; C. Forbes.; J. Sivenius, P. Smets.; A. Lowenthal. European Stroke Prevention Study 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke.Journal of the Neurological Sciences. 1996, 143 (1-2),1-13 .

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,3346
Code tarifaire harmonisé
2933.59
TSCA
No
RTECS
KK7450000

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Analytique et matériel de laboratoire