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1115-70-4 - 1,1-Dimethylbiguanide hydrochloride - Metformin hydrochloride - J63361 - Alfa Aesar

J63361 1,1-Dimethylbiguanide hydrochloride

Numéro CAS
1115-70-4
Synonymes
Metformin hydrochloride

Dimensions Prix ($) Quantité Disponibilité
5g 26,60
25g 77,10
100g 230,00
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1,1-Dimethylbiguanide hydrochloride

MDL
MFCD00012582
EINECS
214-230-6

Propriétés chimiques

Formule
C4H11N5•HCl
Poids formulaire
165.62
Forme
Powder
Point de fusion
218-226°
Solubilité
Soluble in water (50 mg/ml), ethanol, and DMSO (50 mM).

Applications

1,1-Dimethylbiguanide hydrochloride is used as an antidiabetic agent, used in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics, used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Références bibliographiques

Cinquina, A.L.; Longo, F.; Calı?, A.; De Santis, L.; Baccelliere, R.; Cozzani, R.Validation and comparison of analytical methods for the determination of histamine in tuna fish samples. Journal of Chromatography A.2004, 1032, (1-2), 79-85.

Nobuyuki Yasuda.; Takashi Inoue.; Tadashi Nagakura.; Kazuto Yamazaki.; Kazunobu Kira.; Takao Saeki.; Isao Tanaka. Enhanced secretion of glucagon-like peptide 1 by biguanide compounds. Biochemical and Biophysical Research Communications.2002, 298, (5), 779-784.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H315-H319

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Mentions de prudence: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,5938
Code tarifaire harmonisé
2925.29
TSCA
No
RTECS
DU1800000

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Catalyseurs

Analytique et matériel de laboratoire