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1177-87-3 - Dexamethasone acetate - J63691 - Alfa Aesar

J63691 Dexamethasone acetate

Numéro CAS
1177-87-3
Synonymes

Dimensions Prix ($) Quantité Disponibilité
250mg 13,57
1g 42,15
5g 134,06
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Dexamethasone acetate

MDL
MFCD00027407
EINECS
214-646-8

Propriétés chimiques

Formule
C24H31FO6
Poids formulaire
434.50
Forme
Powder
Point de fusion
240°
Solubilité
Soluble at 100 mg/ml in acetone

Applications

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts of the body. To treat or prevent allergic reactions. As treatment of certain kinds of autoimmune diseases, skin conditions, asthma and other lung conditions. As treatment for a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It is also used for replacement therapy in adrenal insufficiency and in a screening test for the diagnosis of cushing's syndrome. Dexamethasone Acetate has also been determined to markedly decrease the number of activated macrophages. In addition, Dexamethasone Acetate has been observed to significantly decrease mRNA levels of TPH2 (tryptophan hydroxylase-2) in the raphe nuclei of C57/Bl6 mice.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Références bibliographiques

Leibowitz HM,; Kupferman A,; Stewart RH,; Kimbrough RL.Evaluation of dexamethasone acetate as a topical ophthalmic formulation. . Am J Ophthalmol. . 1978, 86 (3), 418-23..

Roberts CP,; Murphy AA,; Santanam N,; Parthasarathy S. The effect of RU 486 and related compounds on cultured macrophage differentiation and function. Am J Obstet Gynecol.. 1996, 175 (2), 248-57.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H317

May cause an allergic skin reaction.

Mentions de prudence: P261-P280-P272-P363-P321-P333+P313-P302+P352-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Contaminated work clothing should not be allowed out of the workplace. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,2943
Beilstein
2342608
Code tarifaire harmonisé
2937.22
TSCA
Yes
RTECS
TU4050000

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Consulté récemment

Produits chimiques

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Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire