Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

303-45-7 - Gossypol, 98+% - Thespesin - 2,2'-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene) - J63767 - Alfa Aesar

J63767 Gossypol, 98+%

Numéro CAS
303-45-7
Synonymes
Thespesin
2,2'-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)

Dimensions Prix ($) Quantité Disponibilité
25mg 59,60
100mg 138,00
250mg 270,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Gossypol, 98+%

MDL
MFCD00017352

Propriétés chimiques

Formule
C30H30O8
Poids formulaire
518.56
Forme
Powder
Solubilité
Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties.

Applications

Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Références bibliographiques

M.C. Chang,; Zhiping Gu (Chi-ping Ku),; S.K. Saksena. Effects of Gossypol on the fertility of male rats, hamsters and rabbits. Contraception. 1980, 21(5), 461-469.

Ying-Bo Mao,; Wen-Juan Cai,; Jia-Wei Wang,; Gao-Jie Hong. Silencing a cotton bollworm P450 monooxygenase gene by plant-mediated RNAi impairs larval tolerance of gossypo. Nature Biotechnology. 2007 , 251307 - 1313 .

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H341-H361-H302

Suspected of causing genetic defects. Suspected of damaging fertility or the unborn child. Harmful if swallowed.

Mentions de prudence: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,4528
Code tarifaire harmonisé
2912.49
TSCA
No
RTECS
DU3100000

Recommandé

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire