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99011-02-6 - Imiquimod, 99% - J63990 - Alfa Aesar

J63990 Imiquimod, 99%

Numéro CAS
99011-02-6
Synonymes

Dimensions Prix ($) Quantité Disponibilité
100mg 99,20
1g 294,58
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Imiquimod, 99%

MDL
MFCD00866946

Propriétés chimiques

Formule
C14H16N4
Poids formulaire
240.31
Forme
Solid
Point de fusion
292-294°
Solubilité
Soluble in dimethyl sulfoxide and dimethyl formamide. Slightly soluble in water. Insoluble in ethanol.

Applications

Imiquimod is a caspase 3 activator which acts as an immunomodulator and displays antiviral and anti-tumor activity. It is a patient-applied cream used for the treatment of genital warts and basal cell carcinoma. It is also used to cure actinic keratosis on the face and scalp. It belongs to a group of drugs called immune response modifiers, which work by activating the immune system to fight abnormal skin growth.

Notes

Store in cool place. Incompatible with strong oxidizing agents.

Références bibliographiques

Arits, A., Nelemans, P.; Smeets, N. K. Response to ‘Photodynamic therapy versus topical imiquimod versus topical fluorouracil for treatment of superficial basal-cell carcinoma: a single blind, non-inferiority, randomised controlled trial: a critical appraisal’. Br. J. Dermatol. 2015, 172 (1), 11-12.

Kono, T.; Biswas, G.; Fall, J.; Mekata, T.; Hikima, J. I.; Itami, T.; Sakai, M. Adjuvant effects of poly I: C and imiquimod on the immunization of kuruma shrimp (Marsupenaeus japonicus) with a recombinant protein, VP28 against white spot syndrome virus. Aquaculture 2015, 446, 236-241.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,4922
Classe de danger
6.1
Groupe d'emballage
III
Code tarifaire harmonisé
2933.99
TSCA
No

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Consulté récemment

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