Insulin, human, from yeast, BT-243 is used in cell culture applications. It is employed as a drug to control insulin-dependent diabetes mellitus. Further, it is used to stimulate growth and proliferation of cultured cells as well as to investigate insulin activity on sensitive cells used in research studies. In addition to this, it serves as a component of serum-free media formulations for most primary cells and cell lines.
Ahmad, A.; Othman, I.; Zaini Md Zain, A.; Hoque Chowdhury, E. Controlled Release of Insulin in Blood from Strontium-Substituted Carbonate Apatite Complexes. Curr. Drug Deliv. 2015, 12 (2), 210-222.
Franzè, S.; Cilurzo, F.; Minghetti, P. Insulin Biosimilars: The Impact on Rapid-Acting Analogue-Based Therapy. Biodrugs 2015, 29 (2), 113-121.