Z-Val-Val-Nle diazomethyl ketone
Solubility in dimethyl sulfoxide (10 mg/ml) and water.
Z-Val-Val-Nle diazomethyl ketone is used as an irreversible cathepsin inhibitor that is 380 times more effective in inactivating cathepsin S than L. It is often abbreviated as DMK. Peptidyl diazomethyl ketones are specific inactivators of thiol proteinases.
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.