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9025-26-7 - Cathepsin D, human liver - EC - J66506 - Alfa Aesar

J66506 Cathepsin D, human liver

Numéro CAS

Dimensions Prix ($) Quantité Disponibilité
25microg 122,00
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Cathepsin D, human liver


Propriétés chimiques

Reconstitute in water at 1µg/µl


Cathepsin D, human liver is useful for inhibitor screening, kinetic studies, and cleavage of substrates in vitro or in tissue culture. It contains the mannose-6-phosphate lysosomal localization signal that targets the enzyme to the lysosomal compartment where it functions in the normal degradation of proteins. It is a useful prognostic indicator for breast cancer.


A lyophilized powder containing phosphate buffer salt. Activity is greater than 300 units per mg protein. One unit will product an increase of A280 of 1.0 per 60 minutes at 37°C, measured as TCA-soluble products using acid-denatured hemoglobin as substrate.

Références bibliographiques

J Higaki, R Catalano; A W Guzzetta; D Quon; J F Navé; C Tarnus; H D'Orchymont; B Cordell. Processing of beta-amyloid precursor protein by cathepsin D. Journal of Biological Chemistry.1993, 271, (50), 31885-31893.

A J Barrett. Cathepsin D. Purification of isoenzymes from human and chicken liver. Biochemical Journal.1970, 117, (3), 601-607.

Mentions de danger et de prudence du SGH

Mentions de prudence: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé


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    3-Chloro-2-fluorobenzonitrile, 97%
  • H59224

    5-Bromopyridine-3-carboxaldehyde, 97%
  • J60039

  • 35969

    Low Form Nickel Crucible;Cap (ml), 45;Top Dia (mm), 46;Bottom Dia (mm), 38;Depth (mm), 35
  • H27716

    2-Hydroxy-6-methylpyridine-4-carboxylic acid, 97%

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux


Analytique et matériel de laboratoire