5Z-7-oxozeaenol acts as an irreversible ATP-competitive inhibitor of ERK2 (IC<sub>50</sub> = 80 nM). It also inhibits TAK1 (MEKK7), MKK7, and MEK1, which all contain a common cysteine residue in the ATP-binding site. 5Z-7-oxozeaenol does not inhibit other MAP kinases.
Mentions de danger (UE): H301
Toxic if swallowed.
Mentions de prudence: P260-P201-P280-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.