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60-24-2 - 2-Mercaptoethanol, Electrophoresis Grade, 98+% - Thioethylene glycol - Thioglycol - J66742 - Alfa Aesar

J66742 2-Mercaptoethanol, Electrophoresis Grade, 98+%

Numéro CAS
60-24-2
Synonymes
Thioethylene glycol
Thioglycol

Dimensions Prix ($) Quantité Disponibilité
250g 23,80
1000g 64,90
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2-Mercaptoethanol, Electrophoresis Grade, 98+%

MDL
MFCD00004890
EINECS
200-464-6

Propriétés chimiques

Formule
C2H6OS
Poids formulaire
78.13
Forme
Liquid
Point de fusion
-100°
Point d'ébullition
156-158°
Point d'éclair
73°(163°F)
Densité
1.114
Sensibilité
Air Sensitive & Hygroscopic
Solubilité
Fully miscible in water. Soluble in alcohol, ether, benzene, and other organic solvents.

Applications

β-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been commonly used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA. It is widely used for retarding oxidation of biological compounds in solution.

Notes

Handle under dry protective gas. Store in cool condition. Incompatible with air, moisture, oxidizing agents.

Références bibliographiques

Margaret L. Heidrick..; Linda C. Hendricks.; David E. Cook. Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice. Mechanisms of Ageing and Development. 1984, 27 (3),341-358 .

B. Tasheva.; G. Dessev. Artifacts in sodium dodecyl sulfate-polyacrylamide gel electrophoresis due to 2-mercaptoethanol.Anal. Biochem. 1983, 129 (1),98-102 .

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H227-H301-H310-H315-H318-H317-H335

Combustible liquid. Toxic if swallowed. Fatal in contact with skin. Causes skin irritation. Causes serious eye damage. May cause an allergic skin reaction. May cause respiratory irritation.

Mentions de prudence: P210u-P261-P262-P280-P301+P310a-P305+P351+P338-P304+P340-P312a-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Do not get in eyes, on skin, or on clothing. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,5869
Beilstein
773648
Classe de danger
6.1
Groupe d'emballage
II
Code tarifaire harmonisé
2930.90
TSCA
Yes
RTECS
KL5600000

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