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60-24-2 - 2-Mercaptoethanol, Electrophoresis Grade, 98+% - Thioethylene glycol - Thioglycol - J66742 - Alfa Aesar

J66742 2-Mercaptoethanol, Electrophoresis Grade, 98+%

Numéro CAS
60-24-2
Synonymes
Thioethylene glycol
Thioglycol

Dimensions Prix ($) Quantité Disponibilité
250g 25,03
1000g 52,96
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2-Mercaptoethanol, Electrophoresis Grade, 98+%

MDL
MFCD00004890
EINECS
200-464-6

Propriétés chimiques

Formule
C2H6OS
Poids formulaire
78.13
Forme
Liquid
Point de fusion
-100°
Point d'ébullition
156-158°
Point d'éclair
73°(163°F)
Densité
1.114
Sensibilité
Air Sensitive & Hygroscopic
Solubilité
Fully miscible in water. Soluble in alcohol, ether, benzene, and other organic solvents.

Applications

β-Mercaptoethanol can act as an enzyme reactivator in systems necessitating reduction for activation, and has been commonly used to reduce disulfide bonds in order to separate protein subunits for use in electrophoresis. This product can also be used to form o-Phthalaldehyde-beta-mercaptoethanol (OPAME), a fluorogenic reagent shown to detect amino acids based on its reaction with primary amines. More recently OPAME has been used to distinguish between ssDNA/dsDNA and even single base mismatches in the hybridization of DNA. It is widely used for retarding oxidation of biological compounds in solution.

Notes

Handle under dry protective gas. Store in cool condition. Incompatible with air, moisture, oxidizing agents.

Références bibliographiques

Margaret L. Heidrick..; Linda C. Hendricks.; David E. Cook. Effect of dietary 2-mercaptoethanol on the life span, immune system, tumor incidence and lipid peroxidation damage in spleen lymphocytes of aging BC3F1 mice. Mechanisms of Ageing and Development. 1984, 27 (3),341-358 .

B. Tasheva.; G. Dessev. Artifacts in sodium dodecyl sulfate-polyacrylamide gel electrophoresis due to 2-mercaptoethanol.Anal. Biochem. 1983, 129 (1),98-102 .

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H301-H310-H315-H317-H335-H318-H400-H410-H227

Toxic if swallowed. Fatal in contact with skin. Causes skin irritation. May cause an allergic skin reaction. May cause respiratory irritation. Causes serious eye damage. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects. Combustible liquid.

Mentions de prudence: P210-P261-P262-P273-P301+P310-P305+P351+P338-P361-P302+P350-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Do not get in eyes, on skin, or on clothing. Avoid release to the environment. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Remove/Take off immediately all contaminated clothing. IF ON SKIN: Gently wash with plenty of soap and water. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,5869
Beilstein
773648
Classe de danger
6.1
Groupe d'emballage
II
Code tarifaire harmonisé
2930.90
TSCA
Yes
RTECS
KL5600000

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Analytique et matériel de laboratoire