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67-66-3 - Chloroform, Molecular Biology Reagent - Trichloromethane - J67241 - Alfa Aesar

J67241 Chloroform, Molecular Biology Reagent

Numéro de CAS
67-66-3
Synonymes
Trichloromethane

Conditionnement Prix ($) Quantité Disponibilité
500ml 53,80
1L 90,30
2.5L 184,00
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Chloroform, Molecular Biology Reagent

MDL
MFCD00000826
EINECS
200-663-8

Propriétés chimiques

Formule
CHCl3
Poids moleculaire
119.38
Forme
Liquid
Point de fusion
-63°
Point d'ébullition
61°
Densité
1.492
Indice de réfraction
1.446
Solubilité
Soluble in water at 20°C 8 g/L.

Applications

Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.

Notes

Stabilized with approx. 50 ppm amylene

Références bibliographiques

Auttachoat W, et al. Immunotoxicological profile of chloroform in female B6C3F1 mice when administered in drinking water.Drug Chem. Toxicol.,2009,32(1), 77-87.

Lin YR, et al. Role of ryanodine receptors in chloroform-induced contraction in Swine tracheal smooth muscle.Toxicol Appl Pharmacol.,2002,183(2), 146-51.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H302-H331-H315-H319-H351-H361-H372

Harmful if swallowed. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. Suspected of causing cancer. Suspected of damaging fertility or the unborn child. Causes damage to organs through prolonged or repeated exposure.

Mentions de prudence: P260-P201-P280-P305+P351+P338-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,2141
Beilstein
1731042
Classe de danger
6.1
Groupe d'emballage
III
Code tarifaire harmonisé
2903.13
TSCA
Yes
RTECS
FS9100000

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Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire