Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

67-66-3 - Chloroform, Molecular Biology Reagent - Trichloromethane - J67241 - Alfa Aesar

J67241 Chloroform, Molecular Biology Reagent

Numéro CAS
67-66-3
Synonymes
Trichloromethane

Dimensions Prix ($) Quantité Disponibilité
500ml 54,28
1L 91,16
2.5L 180,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

Chloroform, Molecular Biology Reagent

MDL
MFCD00000826
EINECS
200-663-8

Propriétés chimiques

Formule
CHCl3
Poids formulaire
119.38
Forme
Liquid
Point de fusion
-63°
Point d'ébullition
61°
Densité
1.492
Indice de réfraction
1.446
Solubilité
Soluble in water at 20°C 8 g/L.

Applications

Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.

Notes

Stabilized with approx. 50 ppm amylene

Références bibliographiques

Auttachoat W, et al. Immunotoxicological profile of chloroform in female B6C3F1 mice when administered in drinking water.Drug Chem. Toxicol.,2009,32(1), 77-87.

Lin YR, et al. Role of ryanodine receptors in chloroform-induced contraction in Swine tracheal smooth muscle.Toxicol Appl Pharmacol.,2002,183(2), 146-51.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H351-H361-H373-H302-H332-H315-H336

Suspected of causing cancer. Suspected of damaging fertility or the unborn child. May cause damage to organs through prolonged or repeated exposure. Harmful if swallowed. Harmful if inhaled. Causes skin irritation. May cause drowsiness or dizziness.

Mentions de prudence: P260-P201-P261-P280-P281-P304+P340-P362-P301+P312-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,2141
Beilstein
1731042
Classe de danger
6.1
Groupe d'emballage
III
Code tarifaire harmonisé
2903.13
TSCA
Yes
RTECS
FS9100000

Recommandé

  • 12337

    Tungsten(VI) chloride, 99%
  • A19782

    4-Bromo-2-chloro-1-fluorobenzene, 98+%
  • 39112

    Silicon plate, 6.35mm (0.25in) thick, 99.999% (metals basis)
  • L12099

    Sorbitan monolaurate
  • H63941

    3-(3-Pyridyl)-L-alanine, 98%

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire