Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

75621-03-3 - CHAPS, Electrophoresis Grade - 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate - J67359 - Alfa Aesar

J67359 CHAPS, Electrophoresis Grade

Numéro CAS
75621-03-3
Synonymes
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Dimensions Prix ($) Quantité Disponibilité
5g 86,57
10g 175,88
25g 429,00
Ajouter au panier Ajouter au devis en vrac Afficher l'article

CHAPS, Electrophoresis Grade

MDL
MFCD00012116

Propriétés chimiques

Formule
C32H58N2O7S
Poids formulaire
614.88
Forme
Powder
Point de fusion
156-158°
Sensibilité
Hygroscopic
Solubilité
Soluble in water (10 mg/ml). Soluble in DMF and hot methanol.

Applications

CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. It is suitable for isolation of membrane proteins with the following features such as sufficient protein solubilization capability, no denaturing or inactivation of proteins, no interference with protein activities, no precipitation at 4°C, appropriate critical micelle concentrations (CMC) and micelle size, no absorption in the UV region, no toxicity and availability of detergent detection methods.

Notes

Hygroscopic. Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

Références bibliographiques

Jacob Anglister, et. al. Isotope-edited multidimensional NMR of calcineurin B in the presence of the non-deuterated detergent CHAPS.J. Biomol. NMR.,1993,3(1), 121-126.

F. Anne Stephenson and Richard W. Olsen. Solubilization by CHAPS Detergent of Barbiturate-Enhanced Benzodiazepine-GABA Receptor Complex.J. Neurochem.,1982,39(6), 1579-1586.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé
2924.29
TSCA
No

Recommandé

  • H52865

    4-n-Butoxybenzeneboronic acid, 98%
  • J66930

    1,2,3,5-Tetra-O-benzoyl-2-C-methyl-beta-D-ribofuranose, 98%
  • H66050

    1-Ethyl-1-methylpyrrolidinium bromide, 98%
  • A10332

    3-Chlorobenzylideneacetone, 98%
  • L19655

    2-Fluoro-3-methoxybenzeneboronic acid, 97%

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire