Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

3222-47-7 - 6-Methylnicotinic acid, 99% - 6-Methylpyridine-3-carboxylic acid - L08877 - Alfa Aesar

L08877 6-Methylnicotinic acid, 99%

Numéro CAS
3222-47-7
Synonymes
6-Methylpyridine-3-carboxylic acid

Dimensions Prix ($) Quantité Disponibilité
1g 28,11
5g 89,30
25g 402,30
Ajouter au panier Ajouter au devis en vrac Afficher l'article

6-Methylnicotinic acid, 99%

MDL
MFCD00006341
EINECS
000-000-0

Propriétés chimiques

Formule
C7H7NO2
Poids formulaire
137.14
Point de fusion
210-215°
Solubilité
Sparingly soluble in water.

Applications

6-Methylnicotinic acid is an intermediate of the drug etoricoxib (a non- steroidal anti-inflammatory drug for the treatment of arthritis and osteoarthritis). It is also used as organic intermediates.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. Store away from oxidizing agents.

Références bibliographiques

Andreas Tinschert; Andreas Kiener; Klaus Heinzmann; A. Tschech. Isolation of new 6-methylnicotinic-acid-degrading bacteria, one of which catalyses the regioselective hydroxylation of nicotinic acid at position C2.Archives of Microbiology.1997, 168 355-361.

B.-M. Kukovec; Z. Popovic and G. Pavlovic. A new coordination mode of 6-methyl­nicotinic acid in trans-tetra­aquabis­(6-methyl­pyridine-3-carboxyl­ato-[kappa]O)cobalt(II) tetra­hydrate.Acta Cryst.2007, C63 m615-m617.

Dilithiation can be effected with LDA, allowing substitution at the 6-methyl group, as, for example carboxylation in the synthesis of methotrexate analogues: J. Med. Chem., 40, 370 (1997).

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
112049
Code tarifaire harmonisé
2933.39
TSCA
No

Recommandé

  • A11223

    6-Aminonicotinic acid, 98%
  • A12683

    Nicotinic acid, 99%
  • B22873

    Cystamine dihydrochloride, 97+%
  • L19845

    2-Aminopyridine-4-carboxylic acid, 96%
  • H33003

    2-Methyl-6-(trifluoromethyl)nicotinic acid, 97%

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire