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3222-47-7 - 6-Methylnicotinic acid, 99% - 6-Methylpyridine-3-carboxylic acid - L08877 - Alfa Aesar

L08877 6-Methylnicotinic acid, 99%

Numéro CAS
6-Methylpyridine-3-carboxylic acid

Dimensions Prix ($) Quantité Disponibilité
1g 34,10
5g 101,00
25g 402,00
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6-Methylnicotinic acid, 99%


Propriétés chimiques

Poids formulaire
Point de fusion
Sparingly soluble in water.


6-Methylnicotinic acid is an intermediate of the drug etoricoxib (a non- steroidal anti-inflammatory drug for the treatment of arthritis and osteoarthritis). It is also used as organic intermediates.


Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. Store away from oxidizing agents.

Références bibliographiques

Andreas Tinschert; Andreas Kiener; Klaus Heinzmann; A. Tschech. Isolation of new 6-methylnicotinic-acid-degrading bacteria, one of which catalyses the regioselective hydroxylation of nicotinic acid at position C2.Archives of Microbiology.1997, 168 355-361.

B.-M. Kukovec; Z. Popovic and G. Pavlovic. A new coordination mode of 6-methyl­nicotinic acid in trans-tetra­aquabis­(6-methyl­pyridine-3-carboxyl­ato-[kappa]O)cobalt(II) tetra­hydrate.Acta Cryst.2007, C63 m615-m617.

Dilithiation can be effected with LDA, allowing substitution at the 6-methyl group, as, for example carboxylation in the synthesis of methotrexate analogues: J. Med. Chem., 40, 370 (1997).

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Mentions de prudence: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Code tarifaire harmonisé


  • A11223

    6-Aminonicotinic acid, 98%
  • A12683

    Nicotinic acid, 99%
  • B22873

    Cystamine dihydrochloride, 97+%
  • L19845

    2-Aminopyridine-4-carboxylic acid, 96%
  • H33003

    2-Methyl-6-(trifluoromethyl)nicotinic acid, 97%

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